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Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania.
Nat Commun. 2019 Dec 9;10(1):5627. doi: 10.1038/s41467-019-13344-6.
Nat Commun. 2019.
PMID: 31819054
Free PMC article.
Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides.
Padmanabhan PK, Ferreira GR, Zghidi-Abouzid O, Oliveira C, Dumas C, Mariz FC, Papadopoulou B.
Padmanabhan PK, et al.
Nucleic Acids Res. 2021 Sep 20;49(16):9459-9478. doi: 10.1093/nar/gkab667.
Nucleic Acids Res. 2021.
PMID: 34358325
Free PMC article.
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New insights in the mode of action of anti-leishmanial drugs by using chemical mutagenesis screens coupled to next-generation sequencing.
Bhattacharya A, Bigot S, Padmanabhan PK, Mukherjee A, Coelho A, Leprohon P, Papadopoulou B, Ouellette M.
Bhattacharya A, et al. Among authors: padmanabhan pk.
Microb Cell. 2020 Jan 21;7(2):59-61. doi: 10.15698/mic2020.02.708.
Microb Cell. 2020.
PMID: 32025514
Free PMC article.
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DDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania.
Padmanabhan PK, Zghidi-Abouzid O, Samant M, Dumas C, Aguiar BG, Estaquier J, Papadopoulou B.
Padmanabhan PK, et al.
Cell Death Dis. 2016 Oct 13;7(10):e2406. doi: 10.1038/cddis.2016.315.
Cell Death Dis. 2016.
PMID: 27735940
Free PMC article.
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